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Transformation Program

Fortify
Protective Recovery

Ignite
Healthy Slimming

Optimize
Metabolic Liberator

Read Detail on Each Ingredient Below:

Fortify
SUPPLEMENT FACTS
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %Daily Value
Vitamin D 1,000IU 250%
Zinc 20mg 133%
Selenium 35mcg 50%
Manganese 1mg 50%
Chromium 60mcg 50%
Recovery Blend 470mg +
Rhodiola Rosea extract, Cordyceps sinensis mycelia extract, Curcumin(as turmeric 4:1 ext), Olive (Olea europaea) leaf extract
Immune Blend 460mg +
Transfer Factor, Reishi(Ganoderma lucidum) Mushroom extract, Baker's yeast (Saccharomyces cerevisiae) extract
+ Daily Value not established.
Other Ingredients: Vegetarian capsule
Optimize
SUPPLEMENT FACTS
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %Daily Value
Niacin(B3) 20 mg 100%
Pyridoxine (B6) 2mg 100%
Folate (B9) 400mcg 100%
Cyanocobalamine (B12) 6mcg 100%
Iodine 150mcg 100%
Metabolic Blend 488mg +
Acetyl-L-Carnitine, Berberine, Brown Kelp (Ascophyllum Nodosum / Laminara Digitata). L-Theannine, Green Tea (Camellia sinensis) extract
Protective Blend 540mg +
Alpha LipoicAcid, Taurine, Theanine, Resveratrol, Quercetin Dihydrate
+ Daily Value not established.
Other Ingredients: Vegetarian capsule
Ignite
SUPPLEMENT FACTS
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %Daily Value
Vitamin D 1,000IU 250%
Fat Burner Blend 677mg +
Irvingia gabonesis extract, Cissus quadrangularis extract, Sinetrol citrus extract, Bitter Orange, Black Pepper (Piper nigrum) extract
GoActive Blend 380mg +
Green Tea (Camellia sinensis) Extract, Octodrine
+ Daily Value not established.
Other Ingredients: Vegetarian capsule



Ingredients in Improves Focus:

Guarana Seed Extract

 

Guarana is a climbing plant in the maple family, Sapindaceae, native to the Amazon basin and commonly found in Brazil. Guarana has large leaves and clusters of flowers, and is best known for the seeds from its fruit, which are about the size of a coffee bean.

Guarana seed is an effective stimulant as it contains about twice the concentration of caffeine found in coffee seeds (about 2–4.5% caffeine in guarana seeds, compared to 1–2% for coffee seeds).

Octodrine (aka.. DMHA or 2-Aminoisoheptane)

Octodrine (Also known as DMHA, 2-Aminoisoheptane)

Octodrine, also known as DMHA, is an extract derived from the fruit of the Kigelia Africana plant which has been a part of the South, central and West African diet since prehistoric times.

Used in traditional African medicine, the Kigelia Africana plant was prized for its anti-inflammatory 6a, pain relieving 5a - as well as respiratory benefits, which led to the commercial use of Octodrine in the 1950’s as a decongestant. 8a,10b

Energy Boosting Benefits

Octodrine is rapidly gaining popularity for its energy and mood boosting capabilities. This has made it particularly popular as a preworkout supplement since it has several qualities that ensure you get the most out of your workout: boosted energy levels (making it easier to push yourself and move more, which means more calories burned!), increased motivation (lots of energy doesn’t mean anything if you don’t have the desire to work out), and improved mood (when you feel good during and after your workout - it makes it more likely you will come back and do it all over again). Some other benefits include greater pain tolerance 5,6,  decreased rate of perceived exertion 5,6, and improving bronchodilation 3b,4b,5b - which come in handy when lifting weights, powering through a spin or HIIT class, or even wrangling kids and a house full of chores.

One of the best parts about Octodrine is that these benefits kick in fast thanks to its molecular structure. The addition of a methyl group on the alpha carbon increases the amphiphilic nature of the compound — which makes it both water-soluble and lipid-soluble. Increased lipid solubility dramatically increases its ability to pass through the blood brain barrier where it is able to exert its focus-enhancing and euphoric effects.8,9

Weight Loss Benefits

Octodrine can also help boost weight loss due to its ability to decrease appetite as well as improve your mood by increasing the hormones responsible for making you "feel good"4b,5b (say goodbye to binge sessions caused by stress and feeling down!) .

Octodrine’s mood boosting benefits stem from its ability to increase dopamine and norepinephrine levels, which are responsible for enhanced euphoria and wakefulness.3b,4b,5b,6b. Similar in structure and metabolically related to the classical monoamine neurotransmitters, Octodrine can activate trace amine associated receptor 1, while temporarily preventing the reuptake of dopamine and norepinephrine into the presynaptic nerve - improving its “punch” and lasting ability.

In addition, users of DMHA have reported a higher pain threshold and reduced fatigue, thus allowing users to gain maximum benefits from their workouts. Octodrine also induces motivation to do something. As already stated, DMHA triggers the release of dopamine. Dopamine levels influence motivation levels and the subsequent volition. Motivation is the desire to accomplish something while volition is the commitment. A person may wish to achieve something, but if they encounter hurdles along the way, then they may give up. However, if a person has volition, then they will not dissuaded from the cause until they achieve what they set out to do. Thankfully, dopamine, whose release is triggered by the intake of DMHA, ensures you have both the motivation and the volition to achieve your goals.

The combination of effects experienced when using DMHA provide the ultimate support for workouts, hence its increased inclusion in a variety of performance based, pre-workout supplements and drinks.

Pain Relief and Antiinflammatory benefits

Octodrine’s pain relieving and anti-inflammatory benefits extend beyond the ability to improve the benefits of a workout. It can also be useful for reducing daily aches and pains that can prevent or discourage one from doing things around the house, yard, or at work. The better you feel, the more you are able to get done.

(5) In a study performed in 2007 at the University of Benin, researchers confirmed the antiinflammatory and pain relieving benefits of Octodrine/Kigelia Africana extract. On mice and guinea pigs treated with the extract, they found a reduction of redness on irritated paws as well as a higher pain tolerance. Higher doses of the extract showed greater improvement.

(6) Additional studies were performed by John A. Wilkinson to determine the benefits of extracts derived from the fruit of the Kigelia Africana. Researchers, testing the extract on human neutrophils, found that the extract effectively inhibited Cyclooxygenase, which is responsible for converting Arachodonic Acid to pain mediators known as Prostaglandins. Prostaglandins are also responsible for triggering an inflammatory response. Inhibiting the COX and the resulting Prostaglandin production ultimately results in pain relief and reduced inflammation.

Concentration, Focus, and Memory Enhancing Benefits

Preliminary studies show that Octodrine is more effective than its predecessors, DMAA and AMP Citrate, at the ability to improve mental performance 17b,18b,19b. It can keep you alert and focused, allowing you to accomplish more.

Octodrine’s ability to influence the release of dopamine and norepinephrine - which studies show play a role in long term memory and recall, may contribute to improved study or learning efforts.

It also improves episodic memory17b, which, through past experiences, helps one to distinguish between approaches that work from the ones that don’t work. The ability to apply the same logic to solve new challenges saves time and resources.

Effective Against Candida

You may have heard of Candida, but you may not be aware of what a threat it is and the many problems it can cause. Candida albicans is an opportunistic species of yeast, or single-celled fungus, that is the fourth most common hospital-acquired infection in the U.S. and is the most common cause of fatal fungal infections in humans - costing around $2–4 billion dollars a year to treat.

Many people carry a Candida infection or overgrowth without realizing it. Some common symptoms associated with Candida are:

  1. Feeling tired or worn down - possibly suffering from Chronic Fatigue Syndrome or Fibromyalgia
  2. Digestive Issues such as bloating, diarrhea, or constipation
  3. Autoimmune diseases such as Hashimoto’s thyroiditis, Rheumatoid Arthritis, Ulcerative Colitis, Lupus, Scleroderma, or Multiple Sclerosis
  4. Difficulty concentrating, poor memory, lack of focus, ADD or ADHD
  5. Skin issues such as eczema, psoriasis, hives and rashes
  6. Skin and nail fungal infections such as athlete’s foot, ringworm, and toenail fungus
  7. Severe seasonal allergies
  8. Strong sugar or carb cravings
  9. Irritability, mood swings, depression, or anxiety
  10. Vaginal infections, urinary tract infections, rectal itching, or vaginal itching

Candida also has the ability to suppress the immune system so frequent illness or inability to recover quickly from illness may also be a sign.

During efforts to find effective treatments for fighting Candida, it was discovered that Octodrine, in addition to having the ability to fight and kill Candida, also displayed wide-spectrum anti-microbial activity. Compared to other selected anti-Candida drugs, Octodrine was shown to be one of the most effective drugs in killing serum-grown Candida albicans without significantly affecting the survival of host macrophages and skin cells. The fact that no C. albicans mutants showed a decrease in sensitivity to Octodrine argues against the potential emergence of Octodrine-resistant Candida strains - a powerful argument that favors the usage of this drug as a new antifungal treatment against Candida.

Antimicrobial properties of Octodrine

In addition to Octodrine’s ability to kill Candida albicans [2639], it has also displayed some impressive antimicrobial properties - capable of killing Gram-positive as well as Gram-negative bacteria. In one study, Octodrine killed a Uropathagenic strain of E. Coli bacteria after 5 days of exposure, and within a week, it killed everything the scientists tested for. (31b)

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462072/ 
[1] Kigelia africana (Lam.) Benth. http://pza.sanbi.org/kigelia-africana
[2] Comprehensive scientific demystification of Kigelia africana: A review. Olatunji A. Gabriel and Atolani Olubunmi. African Journal of Pure and Applied Chemistry September, 2009, Vol. 3 (9), pp. 158-164, Available online at http://www.academicjournals.org/AJPAC
[3] Kigelia africana (Lam.) Benth. (Sausage tree): Phytochemistry and pharmacological review of a quintessential African traditional medicinal plant. Bello I, Shehu MW, Musa M, Zaini Asmawi M, Mahmud R. J Ethnopharmacol. 2016 Aug 2;189:253-76. doi: 10.1016/j.jep.2016.05.049. Review.
[4] Metabolomic Profiling of Kigelia africana Extracts with Anti-Cancer Activity by High Resolution Tandem Mass Spectroscopy. Pharmacognosy Communications; Oct–Dec 2014, Volume 4, Issue 4, p10-22. Retrieved from http://www98.griffith.edu.au/dspace/bitstream/handle/10072/64248/98347_1.pdf
[5] Analgesic and anti- inflammatory activities of the ethanolic stem bark extract of Kigelia africana
(Bignoniaceae) Omonkhelin. J. Owolabi and Eric. K. I. Omogbai. African Journal of Biotechnology Vol. 6 (5), pp. 582-585, 5 March, 2007 Available online at http://www.academicjournals.org/AJB
[6] Anti-inflammatory and other effects of Kigelia africana extracts. by Dr John A. Wilkinson
Director, Herbal Sciences International Ltd, UK. Consultants to the Natural Products Industry. www.phytochemistry.freeserve.co.uk   www.herbalsciencesinternational.com  www.phytotradeafrica.com
[7]  “The pharmacology of 2-amino-6-methylheptane”; Fellows, E., The Journal of pharmacology and experimental therapeutics; August 1947, 90(4):351-8;; Retrieved from http://www.webcitation.org/6edUQGu7m
[8] The National Museum of American History, Kenneth E. Behring Center; “Eskay’s Oralator”; The Smithsonian Institute; 1984; Retrieved from http://americanhistory.si.edu/collections/search/object/nmah_737864
B)
Lin, C., Chan, T., & Deng, J. “Clinical features and management of herb-induced aconitum poisoning”; Annals of emergency Medicine, 43(5): 574-579; 2004; Retrieved from http://www.sciencedirect.com/science/article/pii/S0196064403011314
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  • Putu Biotec; “Octodrine-CAS No.-543-82-8”; Retrieved from http://www.putubio.com/octodrine-cas-no-543-82-8/
  • The National Museum of American History, Kenneth E. Behring Center; “Eskay’s Oralator”; The Smithsonian Institute; 1984; Retrieved from http://americanhistory.si.edu/collections/search/object/nmah_737864
  • Hutcheon, D, McCullough, L; “The Respiratory Stimulant Action of Octylamines”; British Journal of Pharmacology; 7, 42; 1952; Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.1952.tb00688.x/pdf
  • Charlier, R; “Pharmacology of 2-amino-6-methyl-heptane”; Archives internationales de pharmacodynamie et de thérapie; 85(1-2):144-51; January 1951; Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/14820395
  • Fellows, E; “The pharmacology of 2-amino-6-methylheptane”; The Journal of pharmacology and experimental therapeutics; 90(4):351-8; August 1947; Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/20265812
  •  
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  • Jern, S; “Infusion of epinephrine augments pressor responses to mental stress”; Hypertension; 18(4):467-74; October 1991; Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/1655647
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  • Whitehead, P., Schilling, B., Farney, T., & Bloomer, R; “Impact of a Dietary Supplement Containing 1,3-Dimethylamylamine on Blood Pressure and Bloodborne Markers of Health: a 10-Week Intervention Study”; Nutrition and metabolic insights, 5: 33-39; 2012. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698473/
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  • Sinetrol Citrus Extract

    Sinetrol citrus extract is a patented, proprietary blend of several polyphenolic compounds extracted from various citrus fruits including orange, blood orange, and grapefruit. It combines these bioactive polyphenols, which include narigin, hesperedin and neohesperidin, with guarana extract – whose caffeine content can boost energy and focus. Sinetrol is designed to reduce body fat levels, enhance Lipolysis, reduce waist and hip circumference, and reduce oxidative stress and inflammation. Sinetrol helps to reduce body fat percentage by inhibiting the PDE-4 enzyme, which is responsible for the breakdown of cyclic adenosine monophosphate (cAMP). When a hormone like adrenaline interacts with fat cells, cAMP ensures the proper signal is sent to the enzymes- triggering the release of fatty acids from the cells into the bloodstream to be used for energy. Higher concentrations of cAMP mean more efficient fatty acid release, resulting in improved fat burning and an increase in energy levels.

    Juglans Regia Tree Bark Extract

    Juglans Regia Tree Bark Extract is obtained from the bark of the English Walnut Tree. There are two forms, the naturally derived version scientifically known as 2-amino-5-methylheptane and the cheaper, synthetic version known as 2-amino-6-methylheptane (Octodrine/DMHA). Although very similar in effect, it is believed that the natural version has a better absorption rate and a more potent effect than the synthetic counterpart.

    Juglans Regia Tree Bark Extract Benefits:

    Increased Energy

    One of the key attractions to Juglans Regia Tree Bark Extract is that it provides a smooth and effective boost of energy. It is often used as an alternative to caffeine in an effort to provide a smoother, more comfortable energy without the jitters or subsequent crash associated with high levels of caffeine.

    Increased Pain Threshold

    Another reason Juglans Regia Extract has become popular for use within the body building and fitness industry is that it not only provides extra energy, but it also can increase the pain threshold

    Increased Focus, Concentration, and Energy

    The attraction of Juglans Regia Extract has extended beyond the gym, however, as students are discovering its reputation as a “smart drug” - a supplement that can enhance or improve cognitive functions such as memory, focus, creativity, and motivation. They are using it to help them study longer, remember more, and be more productive. For this reason, it has also become popular for those wanting to get more done around at home or at the office.

    Improved Mood and Motivation

    Juglans Regia Extract has a similar molecular structure to other monoamine releasing agents, which can potentially increase feel good agents such as dopamine and noradrenaline. Higher levels of these monoamines can result in a better mood as well as increased motivation.

    Weight Loss

    The energy boost, increased focus and motivation and heightened pain threshold associated with Juglans Regia supplements can help one push their workouts - resulting in more burned calories at the gym. It is also a thermogenic fat burner that ramps up the metabolic rate and fat burning. It is also a powerful appetite suppressant so it can reduce snacking and other poor eating habits caused by cravings.

    Antioxidant and Anti-inflammatory Benefits

    The benefits of Juglans Regia Extract extend beyond its stimulant and fat burning capabilities.

    Widely used in Ancient Chinese Herbal Medicine, modern medicine has found it to have antioxidant, anti-inflammatory, and anti proliferative properties.
    (https://www.ncbi.nlm.nih.gov/pubmed/17207309)

    Candida Reducing Benefits

    One surprising and little known benefit to Juglans Regia Extract is that it is an effective and safe option to treat Candida overgrowth, a fungal pathogen that can disrupt gut health - affecting nutrient absorption, sugar cravings, inflammation levels, anxiety levels, attention span, as well as other health issues.

    Conclusion

    Juglans Regia has shown in studies to have numerous health benefits.  There are currently no known or published side affects or complications with the ingredient, but as always speak to your doctor before starting or stopping any supplement or medication.

     

    Studies and References:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462072/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628521/
    https://www.ncbi.nlm.nih.gov/pubmed/17207309

     

    *This product has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
    As always, use with a sensible diet and exercise program. Individual results may vary.