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Guarana is a climbing plant in the maple family, Sapindaceae, native to the Amazon basin and commonly found in Brazil. Guarana has large leaves and clusters of flowers, and is best known for the seeds from its fruit, which are about the size of a coffee bean.

Guarana seed is an effective stimulant as it contains about twice the concentration of caffeine found in coffee seeds (about 2–4.5% caffeine in guarana seeds, compared to 1–2% for coffee seeds).

Quercitin is a plant pigment found in various fruits and vegetables with potent antioxidant capabilities quercitin helps counteract the effects of aging and inflammation. Its potent anti-inflammatory benefits can help effectively fight conditions linked to inflammation such as heart disease, arthritis, stomach ulcers, chronic fatigue syndrome, and diabetes.

Quercitin provides natural allergy relief by stabilizing the release of histamines from certain immune cells – resulting in decreased symptoms like watery eyes, runny rose, swollen lips or tongue, and indigestion.

It also helps protect against damage caused by excessive stress levels by suppressing the enzyme necessary for cortisol release, a hormone that produces the “fight or flight” response. During ongoing stress, extended exposure to cortisol can lead to protein breakdown and muscle tissue damage. This combined with its ability to positively affect blood flow and decrease susceptibility to illness after periods of heavy exercise have made it a popular supplement for athletes. In fact, researchers from the School of Applied Physiology at the Georgia Institute of Technology found that, on average, “quercetin provides a statistically significant benefit in human endurance exercise capacity and endurance exercise performance.”

Some foods with the highest concentration of Quercitin in nature are Capers, Onions, Cranberries, and Blueberries.

Juglans Regia Tree Bark Extract is obtained from the bark of the English Walnut Tree. There are two forms, the naturally derived version scientifically known as 2-amino-5-methylheptane and the cheaper, synthetic version known as 2-amino-6-methylheptane (Octodrine/DMHA). Although very similar in effect, it is believed that the natural version has a better absorption rate and a more potent effect than the synthetic counterpart.

Juglans Regia Tree Bark Extract Benefits:

Increased Energy

One of the key attractions to Juglans Regia Tree Bark Extract is that it provides a smooth and effective boost of energy. It is often used as an alternative to caffeine in an effort to provide a smoother, more comfortable energy without the jitters or subsequent crash associated with high levels of caffeine.

Increased Pain Threshold

Another reason Juglans Regia Extract has become popular for use within the body building and fitness industry is that it not only provides extra energy, but it also can increase the pain threshold

Increased Focus, Concentration, and Energy

The attraction of Juglans Regia Extract has extended beyond the gym, however, as students are discovering its reputation as a “smart drug” - a supplement that can enhance or improve cognitive functions such as memory, focus, creativity, and motivation. They are using it to help them study longer, remember more, and be more productive. For this reason, it has also become popular for those wanting to get more done around at home or at the office.

Improved Mood and Motivation

Juglans Regia Extract has a similar molecular structure to other monoamine releasing agents, which can potentially increase feel good agents such as dopamine and noradrenaline. Higher levels of these monoamines can result in a better mood as well as increased motivation.

Weight Loss

The energy boost, increased focus and motivation and heightened pain threshold associated with Juglans Regia supplements can help one push their workouts - resulting in more burned calories at the gym. It is also a thermogenic fat burner that ramps up the metabolic rate and fat burning. It is also a powerful appetite suppressant so it can reduce snacking and other poor eating habits caused by cravings.

Antioxidant and Anti-inflammatory Benefits

The benefits of Juglans Regia Extract extend beyond its stimulant and fat burning capabilities.

Widely used in Ancient Chinese Herbal Medicine, modern medicine has found it to have antioxidant, anti-inflammatory, and anti proliferative properties.
(https://www.ncbi.nlm.nih.gov/pubmed/17207309)

Candida Reducing Benefits

One surprising and little known benefit to Juglans Regia Extract is that it is an effective and safe option to treat Candida overgrowth, a fungal pathogen that can disrupt gut health - affecting nutrient absorption, sugar cravings, inflammation levels, anxiety levels, attention span, as well as other health issues.

Conclusion

Juglans Regia has shown in studies to have numerous health benefits.  There are currently no known or published side affects or complications with the ingredient, but as always speak to your doctor before starting or stopping any supplement or medication.

Studies and References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462072/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628521/
https://www.ncbi.nlm.nih.gov/pubmed/17207309